BMX

BMX
ساختارهای موجود
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EKX, 2YS2, 3SXR, 3SXS
معین‌کننده‌ها
نام‌های دیگر	BMX, ETK, PSCTK2, PSCTK3, BMX non-receptor tyrosine kinase
شناسه‌های بیرونی	OMIM: 300101 MGI: 1101778 HomoloGene: 20411 GeneCards: BMX
Gene location (Human)
Chr.	X chromosome (human)[1]
End	15,556,529 bp[1]
Gene location (Mouse)
Chr.	X chromosome (mouse)[2]
End	164,258,193 bp[2]
الگوی گسترش RNA
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• transferase activity; • nucleotide binding; • protein kinase activity; • signal transducer activity; • metal ion binding; • kinase activity; • GO:0001948 پیوند پروتئینی; • protein tyrosine kinase activity; • signaling receptor binding; • ATP binding; • non-membrane spanning protein tyrosine kinase activity;
ترکیبات سلولی	• سیتوپلاسم; • سیتوزول; • extrinsic component of cytoplasmic side of plasma membrane; • ruffle membrane; • نوکلئوپلاسم; • پوسته یاخته;
فرایند زیستی	• GO:0007243 intracellular signal transduction; • فسفرگیری; • NK T cell differentiation; • transmembrane receptor protein tyrosine kinase signaling pathway; • protein phosphorylation; • cell adhesion; • regulation of cell population proliferation; • peptidyl-tyrosine autophosphorylation; • protein autophosphorylation; • mesoderm development; • دستگاه ایمنی ذاتی; • ورارسانی پیام; • مرگ برنامه‌ریزی‌شده یاخته; • phosphatidylinositol biosynthetic process; • adaptive immune response; • B cell receptor signaling pathway;
	Sources:آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	660
	12169
	ENSG00000102010
	ENSMUSG00000031377
	P51813
	P97504
	NM_203281، NM_001320866، XM_017029752 NM_001721، NM_203281، NM_001320866، XM_017029752
	NM_009759
	NP_001712، NP_975010، XP_016885241 NP_001307795، NP_001712، NP_975010، XP_016885241
	NP_033889
	ویکی‌داده
مشاهده/ویرایش Human	View/Edit Mouse

تیروزین-پروتئین کیناز BMX سیتوپلاسمی (انگلیسی: Cytoplasmic tyrosine-protein kinase BMX‎) یک آنزیم است که در انسان توسط ژن «BMX» کُد می‌شود.[5][6]

این پروتئین با RUFY1 در تعامل است.[7]

منابع

GRCh38: Ensembl release 89: ENSG00000102010 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000031377 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K (December 1994). "BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2". Oncogene. 9 (12): 3683–8. PMID 7970727.
"Entrez Gene: BMX BMX non-receptor tyrosine kinase".
Yang J, Kim O, Wu J, Qiu Y (August 2002). "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking". J. Biol. Chem. 277 (33): 30219–26. doi:10.1074/jbc.M111933200. PMID 11877430.

مشارکت‌کنندگان ویکی‌پدیا. «BMX (gene)». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۱۰ نوامبر ۲۰۱۷.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000102010 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031377 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7970727-5] Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K (December 1994). "BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2". Oncogene. 9 (12): 3683–8. PMID 7970727.

[entrez-6] "Entrez Gene: BMX BMX non-receptor tyrosine kinase".

[pmid11877430-7] Yang J, Kim O, Wu J, Qiu Y (August 2002). "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking". J. Biol. Chem. 277 (33): 30219–26. doi:10.1074/jbc.M111933200. PMID 11877430.